Between 2017 and 2021 GENDERACTION worked to advance gender equality in the European Research Area. We have succeeded in becoming one of the main advocates for gender equality in R&I, by engaging in fruitful discussions with the European Commission, the European Parliament, Council Presidencies, and other stakeholders. We have worked to better include gender equality in Horizon Europe, and have identified new areas for mainstreaming gender, such as Open Science and Open Innovation or international cooperation in science, technology, and innovation. Many of our recommendations have been taken up and put into practice. As a result, our policy briefs have been recognised by the European Commission as one of the most important contributions to gender equality in Horizon 2020.